| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| COQ6 | LCMT1 | ENSAPLP00000013679 | ENSAPLP00000010488 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Leucine carboxyl methyltransferase 1. | 0.509 |
| COQ6 | PUM1 | ENSAPLP00000013679 | ENSAPLP00000009112 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Pumilio RNA binding family member 1. | 0.689 |
| COQ6 | PUM2 | ENSAPLP00000013679 | ENSAPLP00000010338 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Pumilio RNA binding family member 2. | 0.689 |
| COQ6 | RSRC2 | ENSAPLP00000013679 | ENSAPLP00000017706 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Arginine and serine rich coiled-coil 2. | 0.501 |
| COQ6 | SLC25A32 | ENSAPLP00000013679 | ENSAPLP00000002467 | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.833 |
| FLAD1 | MTHFR | ENSAPLP00000032289 | ENSAPLP00000009508 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.514 |
| FLAD1 | SLC25A32 | ENSAPLP00000032289 | ENSAPLP00000002467 | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.639 |
| GLDC | MTHFR | ENSAPLP00000028494 | ENSAPLP00000009508 | Glycine decarboxylase. | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.988 |
| GLDC | SLC25A32 | ENSAPLP00000028494 | ENSAPLP00000002467 | Glycine decarboxylase. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.857 |
| LCMT1 | COQ6 | ENSAPLP00000010488 | ENSAPLP00000013679 | Leucine carboxyl methyltransferase 1. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.509 |
| LCMT1 | SLC25A32 | ENSAPLP00000010488 | ENSAPLP00000002467 | Leucine carboxyl methyltransferase 1. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.723 |
| MTHFR | FLAD1 | ENSAPLP00000009508 | ENSAPLP00000032289 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily. | 0.514 |
| MTHFR | GLDC | ENSAPLP00000009508 | ENSAPLP00000028494 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Glycine decarboxylase. | 0.988 |
| MTHFR | SLC25A32 | ENSAPLP00000009508 | ENSAPLP00000002467 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.547 |
| PCMTD1 | SLC25A32 | ENSAPLP00000019783 | ENSAPLP00000002467 | Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.665 |
| PUM1 | COQ6 | ENSAPLP00000009112 | ENSAPLP00000013679 | Pumilio RNA binding family member 1. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.689 |
| PUM1 | SLC25A32 | ENSAPLP00000009112 | ENSAPLP00000002467 | Pumilio RNA binding family member 1. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.623 |
| PUM2 | COQ6 | ENSAPLP00000010338 | ENSAPLP00000013679 | Pumilio RNA binding family member 2. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.689 |
| PUM2 | SLC25A32 | ENSAPLP00000010338 | ENSAPLP00000002467 | Pumilio RNA binding family member 2. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.623 |
| RGS3 | SLC25A32 | ENSAPLP00000028710 | ENSAPLP00000002467 | Regulator of G protein signaling 3. | Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family. | 0.606 |