node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGF | FGF23 | ENSAPLP00000011666 | ENSAPLP00000002493 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | 0.845 |
EGF | FGFR1 | ENSAPLP00000011666 | ENSAPLP00000013938 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Fibroblast growth factor receptor. | 0.524 |
EGF | FGFR2 | ENSAPLP00000011666 | ENSAPLP00000030490 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Fibroblast growth factor receptor. | 0.747 |
EGF | FGFR3 | ENSAPLP00000011666 | ENSAPLP00000032569 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Fibroblast growth factor receptor. | 0.753 |
EGF | FLT1 | ENSAPLP00000011666 | ENSAPLP00000020030 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.810 |
EGF | FLT3 | ENSAPLP00000011666 | ENSAPLP00000005607 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Fms related tyrosine kinase 3. | 0.738 |
EGF | KDR | ENSAPLP00000011666 | ENSAPLP00000005293 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.857 |
EGF | PDGFRA | ENSAPLP00000011666 | ENSAPLP00000003065 | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.959 |
FGF23 | EGF | ENSAPLP00000002493 | ENSAPLP00000011666 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.845 |
FGF23 | FGFR1 | ENSAPLP00000002493 | ENSAPLP00000013938 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor receptor. | 0.925 |
FGF23 | FGFR2 | ENSAPLP00000002493 | ENSAPLP00000030490 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor receptor. | 0.972 |
FGF23 | FGFR3 | ENSAPLP00000002493 | ENSAPLP00000032569 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor receptor. | 0.957 |
FGF23 | FGFR4 | ENSAPLP00000002493 | ENSAPLP00000026950 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor receptor. | 0.907 |
FGF23 | FLT1 | ENSAPLP00000002493 | ENSAPLP00000020030 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.865 |
FGF23 | FLT3 | ENSAPLP00000002493 | ENSAPLP00000005607 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Fms related tyrosine kinase 3. | 0.847 |
FGF23 | KDR | ENSAPLP00000002493 | ENSAPLP00000005293 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.897 |
FGF23 | KLB | ENSAPLP00000002493 | ENSAPLP00000011106 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Klotho beta. | 0.941 |
FGF23 | PDGFRA | ENSAPLP00000002493 | ENSAPLP00000003065 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. | 0.928 |
FGFR1 | EGF | ENSAPLP00000013938 | ENSAPLP00000011666 | Fibroblast growth factor receptor. | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. | 0.524 |
FGFR1 | FGF23 | ENSAPLP00000013938 | ENSAPLP00000002493 | Fibroblast growth factor receptor. | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. | 0.925 |