Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BAK1BCL2 antagonist/killer 1. (306 aa)    
Predicted Functional Partners:
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
    
 0.999
BCL2
BCL2 apoptosis regulator.
    
0.995
BCL2L1
BCL2 like 1.
    
0.995
ENSAPLP00000030826
Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
    
 0.983
MCL1
MCL1 apoptosis regulator, BCL2 family member.
    
0.968
DIABLO
Uncharacterized protein.
    
 0.950
BCL2L11
BCL2 like 11.
    
 0.941
CAPN2
Calpain 2; Belongs to the peptidase C2 family.
   
 
 0.904
CAPN11
Uncharacterized protein; Belongs to the peptidase C2 family.
   
 
 0.904
BCL2A1
BCL2 related protein A1.
    
 
 0.891
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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