RO60 protein (Anas platyrhynchos) - STRING interaction network

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Score

RO60

Ro60, Y RNA binding protein. (538 aa)

Predicted Functional Partners:

SSB

0.915

PCNA

0.719

COG3

0.694

PUF60

0.690

AGO2

0.674

SNRPC

0.639

HSPA4

0.632

RNASET2

0.613

BICD2

0.603

RPP38

0.569

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGO2	RO60	ENSAPLP00000010261	ENSAPLP00000002596	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	Ro60, Y RNA binding protein.	0.674
BICD2	PUF60	ENSAPLP00000023884	ENSAPLP00000027648	BICD cargo adaptor 2.	Poly(U) binding splicing factor 60.	0.654
BICD2	RO60	ENSAPLP00000023884	ENSAPLP00000002596	BICD cargo adaptor 2.	Ro60, Y RNA binding protein.	0.603
BICD2	RPP38	ENSAPLP00000023884	ENSAPLP00000001477	BICD cargo adaptor 2.	Ribonuclease P/MRP subunit p38.	0.719
COG3	RO60	ENSAPLP00000010663	ENSAPLP00000002596	Component of oligomeric golgi complex 3.	Ro60, Y RNA binding protein.	0.694
HSPA4	RO60	ENSAPLP00000002168	ENSAPLP00000002596	Heat shock protein family A (Hsp70) member 4.	Ro60, Y RNA binding protein.	0.632
PCNA	RO60	ENSAPLP00000028238	ENSAPLP00000002596	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ro60, Y RNA binding protein.	0.719
PCNA	SNRPC	ENSAPLP00000028238	ENSAPLP00000024625	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.535
PUF60	BICD2	ENSAPLP00000027648	ENSAPLP00000023884	Poly(U) binding splicing factor 60.	BICD cargo adaptor 2.	0.654
PUF60	RO60	ENSAPLP00000027648	ENSAPLP00000002596	Poly(U) binding splicing factor 60.	Ro60, Y RNA binding protein.	0.690
PUF60	RPP38	ENSAPLP00000027648	ENSAPLP00000001477	Poly(U) binding splicing factor 60.	Ribonuclease P/MRP subunit p38.	0.723
RNASET2	RO60	ENSAPLP00000010557	ENSAPLP00000002596	Uncharacterized protein; Belongs to the RNase T2 family.	Ro60, Y RNA binding protein.	0.613
RNASET2	SNRPC	ENSAPLP00000010557	ENSAPLP00000024625	Uncharacterized protein; Belongs to the RNase T2 family.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.406
RO60	AGO2	ENSAPLP00000002596	ENSAPLP00000010261	Ro60, Y RNA binding protein.	Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include ago2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...]	0.674
RO60	BICD2	ENSAPLP00000002596	ENSAPLP00000023884	Ro60, Y RNA binding protein.	BICD cargo adaptor 2.	0.603
RO60	COG3	ENSAPLP00000002596	ENSAPLP00000010663	Ro60, Y RNA binding protein.	Component of oligomeric golgi complex 3.	0.694
RO60	HSPA4	ENSAPLP00000002596	ENSAPLP00000002168	Ro60, Y RNA binding protein.	Heat shock protein family A (Hsp70) member 4.	0.632
RO60	PCNA	ENSAPLP00000002596	ENSAPLP00000028238	Ro60, Y RNA binding protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.719
RO60	PUF60	ENSAPLP00000002596	ENSAPLP00000027648	Ro60, Y RNA binding protein.	Poly(U) binding splicing factor 60.	0.690
RO60	RNASET2	ENSAPLP00000002596	ENSAPLP00000010557	Ro60, Y RNA binding protein.	Uncharacterized protein; Belongs to the RNase T2 family.	0.613