Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
NALCNSodium leak channel, non-selective. (1738 aa)    
Predicted Functional Partners:
UNC80
Unc-80 homolog, NALCN channel complex subunit.
   
 0.998
CDH8
Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.
   
  
 0.846
FAM155A-2
Uncharacterized protein.
   
 
 0.837
FAM155B
Family with sequence similarity 155 member B.
   
 
 0.837
SIK3
Uncharacterized protein.
   
  
 0.743
ITSN2
Uncharacterized protein.
      
 0.664
ASIC4
Acid sensing ion channel subunit family member 4; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
      
 0.641
KCNG1
Potassium voltage-gated channel modifier subfamily G member 1; Belongs to the potassium channel family.
    
 
 0.618
SCN3B
Sodium voltage-gated channel beta subunit 3.
    
 0.607
EXOSC10
Exosome component 10.
      
 0.600
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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