RAD18 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

RAD18

RAD18 E3 ubiquitin protein ligase. (501 aa)

Predicted Functional Partners:

PCNA

0.996

POLH

0.979

SHPRH

0.971

SLF1

0.964

U3J5I9_ANAPP

0.954

UBE2V2

0.945

FANCM

0.931

UBE2B

0.927

UBE2A

0.927

RAD52

0.921

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FANCM	PCNA	ENSAPLP00000027475	ENSAPLP00000028238	FA complementation group M.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.973
FANCM	POLH	ENSAPLP00000027475	ENSAPLP00000000581	FA complementation group M.	DNA polymerase eta.	0.597
FANCM	RAD18	ENSAPLP00000027475	ENSAPLP00000002608	FA complementation group M.	RAD18 E3 ubiquitin protein ligase.	0.931
FANCM	RAD52	ENSAPLP00000027475	ENSAPLP00000030267	FA complementation group M.	RAD52 homolog, DNA repair protein.	0.955
FANCM	SHPRH	ENSAPLP00000027475	ENSAPLP00000018859	FA complementation group M.	SNF2 histone linker PHD RING helicase.	0.646
FANCM	SLF1	ENSAPLP00000027475	ENSAPLP00000029800	FA complementation group M.	SMC5-SMC6 complex localization factor 1.	0.737
FANCM	U3J5I9_ANAPP	ENSAPLP00000027475	ENSAPLP00000014766	FA complementation group M.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.534
FANCM	UBE2A	ENSAPLP00000027475	ENSAPLP00000027409	FA complementation group M.	Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.	0.707
FANCM	UBE2B	ENSAPLP00000027475	ENSAPLP00000014685	FA complementation group M.	Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family.	0.707
FANCM	UBE2V2	ENSAPLP00000027475	ENSAPLP00000020539	FA complementation group M.	Ubiquitin conjugating enzyme E2 V2.	0.772
PCNA	FANCM	ENSAPLP00000028238	ENSAPLP00000027475	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	FA complementation group M.	0.973
PCNA	POLH	ENSAPLP00000028238	ENSAPLP00000000581	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase eta.	0.990
PCNA	RAD18	ENSAPLP00000028238	ENSAPLP00000002608	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	RAD18 E3 ubiquitin protein ligase.	0.996
PCNA	RAD52	ENSAPLP00000028238	ENSAPLP00000030267	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	RAD52 homolog, DNA repair protein.	0.901
PCNA	SHPRH	ENSAPLP00000028238	ENSAPLP00000018859	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	SNF2 histone linker PHD RING helicase.	0.959
PCNA	SLF1	ENSAPLP00000028238	ENSAPLP00000029800	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	SMC5-SMC6 complex localization factor 1.	0.519
PCNA	U3J5I9_ANAPP	ENSAPLP00000028238	ENSAPLP00000014766	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.950
PCNA	UBE2A	ENSAPLP00000028238	ENSAPLP00000027409	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.	0.889
PCNA	UBE2B	ENSAPLP00000028238	ENSAPLP00000014685	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family.	0.889
PCNA	UBE2V2	ENSAPLP00000028238	ENSAPLP00000020539	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Ubiquitin conjugating enzyme E2 V2.	0.960