STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPA5Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (652 aa)    
Predicted Functional Partners:
HSP90B1
Heat shock protein 90 beta family member 1.
   
 0.991
HYOU1
Hypoxia up-regulated 1.
  
0.988
U3J188_ANAPP
Uncharacterized protein.
 
 0.977
DNAJB11
J domain-containing protein.
 
 0.971
DNAJC10
Uncharacterized protein.
  
 0.969
MANF
Mesencephalic astrocyte derived neurotrophic factor.
   
 
 0.967
ATF6
Activating transcription factor 6.
    
 0.964
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
   
 0.955
PDIA4
Protein disulfide-isomerase.
   
 0.953
PDIA3
Protein disulfide-isomerase.
   
 0.951
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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