STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAMLD1Mastermind like domain containing 1. (1014 aa)    
Predicted Functional Partners:
FAM118B
Family with sequence similarity 118 member B.
    
 0.762
CREBBP
CREB binding protein.
  
 
  0.612
CAPN15
Calpain 15; Belongs to the peptidase C2 family.
    
 
 0.605
MED8
Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
 0.595
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
      
 0.589
ENSAPLP00000025735
Uncharacterized protein.
     
 0.589
ZNF236
Zinc finger protein 236.
   
 0.575
RBPJL
Recombination signal binding protein for immunoglobulin kappa J region like.
    
 0.571
ENSAPLP00000022103
Brix domain-containing protein.
   
  
 0.563
EP300
E1A binding protein p300.
    
  0.535
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.