Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MAMLD1Mastermind like domain containing 1. (1014 aa)    
Predicted Functional Partners:
CAPN15
Calpain 15; Belongs to the peptidase C2 family.
    
 0.878
MED8
Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
     
 0.873
DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
      
 0.871
ENSAPLP00000025735
Uncharacterized protein.
     
 0.855
ZNF236
Zinc finger protein 236.
   
 0.852
ENSAPLP00000019970
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
   
  
 0.766
FAM118B
Family with sequence similarity 118 member B.
    
 0.687
MTM1
Myotubularin 1.
    
 0.677
CREBBP
CREB binding protein.
  
 
 0.677
ENSAPLP00000024902
EF-hand domain-containing protein.
    
 0.677
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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