Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
IBTKInhibitor of Bruton tyrosine kinase. (1357 aa)    
Predicted Functional Partners:
CUL3
Cullin 3; Belongs to the cullin family.
   
 0.959
ANKRD9
Ankyrin repeat domain 9.
    
 0.874
DNAJC17
DnaJ heat shock protein family (Hsp40) member C17.
      
 0.871
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.727
MICU1
Mitochondrial calcium uptake 1.
      
 0.719
AGK
Acylglycerol kinase.
      
 0.718
U3IDF0_ANAPP
Q_MOTIF domain-containing protein.
    
   0.690
EIF4A2
Eukaryotic translation initiation factor 4A2; Belongs to the DEAD box helicase family.
    
   0.690
ZNF516
Zinc finger protein 516.
    
 0.672
IRAK1BP1
Interleukin 1 receptor associated kinase 1 binding protein 1.
      
 0.670
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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