Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
DDCDopa decarboxylase. (469 aa)    
Predicted Functional Partners:
TH
Tyrosine hydroxylase.
   
 0.971
DBH
Dopamine beta-hydroxylase.
     
 0.965
U3ITA2_ANAPP
BH4_AAA_HYDROXYL_2 domain-containing protein.
   
 0.965
PAH
Phenylalanine hydroxylase.
   
 0.963
TPH2
Tryptophan hydroxylase 2.
   
 0.963
COMT
Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.
   
 
 0.958
ENSAPLP00000032038
Uncharacterized protein.
     
 0.957
TPH1
Uncharacterized protein.
   
 0.956
TDO2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
     
 0.956
AANAT
Aralkylamine N-acetyltransferase.
     
 0.955
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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