Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1396 aa)    
Predicted Functional Partners:
MAP3K1
Mitogen-activated protein kinase kinase kinase 1.
    
0.929
NRK
Uncharacterized protein.
  
  
 
0.901
FGFR1OP2
FGFR1 oncogene partner 2.
    
 
 0.825
TNIK
CNH domain-containing protein.
   
  0.756
ENSAPLP00000023838
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
  0.756
ZRANB1
Zinc finger RANBP2-type containing 1.
    
   0.693
NCK2
Cytoplasmic protein.
    
 
 0.624
ENSAPLP00000017407
Nanos-type domain-containing protein; Belongs to the nanos family.
    
   0.612
STRN
Striatin.
    
 
 0.578
STRN3
Striatin 3.
    
 
 0.576
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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