MAP4K4 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MAP4K4

Mitogen-activated protein kinase kinase kinase kinase 4. (1396 aa)

Predicted Functional Partners:

MAP3K1

0.918

NRK

0.901

STRN3

0.576

STRN4

0.576

TBC1D8

0.483

MAGI3

0.467

ENSAPLP00000029356

0.429

NCK2

0.426

TXN

0.414

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPLP00000029356	MAP4K4	ENSAPLP00000029356	ENSAPLP00000002786	TAF domain-containing protein.	Mitogen-activated protein kinase kinase kinase kinase 4.	0.429
MAGI3	MAP4K4	ENSAPLP00000002142	ENSAPLP00000002786	Membrane associated guanylate kinase, WW and PDZ domain containing 3.	Mitogen-activated protein kinase kinase kinase kinase 4.	0.467
MAGI3	NRK	ENSAPLP00000002142	ENSAPLP00000013098	Membrane associated guanylate kinase, WW and PDZ domain containing 3.	Uncharacterized protein.	0.467
MAP3K1	MAP4K4	ENSAPLP00000024275	ENSAPLP00000002786	Mitogen-activated protein kinase kinase kinase 1.	Mitogen-activated protein kinase kinase kinase kinase 4.	0.918
MAP3K1	NRK	ENSAPLP00000024275	ENSAPLP00000013098	Mitogen-activated protein kinase kinase kinase 1.	Uncharacterized protein.	0.908
MAP4K4	ENSAPLP00000029356	ENSAPLP00000002786	ENSAPLP00000029356	Mitogen-activated protein kinase kinase kinase kinase 4.	TAF domain-containing protein.	0.429
MAP4K4	MAGI3	ENSAPLP00000002786	ENSAPLP00000002142	Mitogen-activated protein kinase kinase kinase kinase 4.	Membrane associated guanylate kinase, WW and PDZ domain containing 3.	0.467
MAP4K4	MAP3K1	ENSAPLP00000002786	ENSAPLP00000024275	Mitogen-activated protein kinase kinase kinase kinase 4.	Mitogen-activated protein kinase kinase kinase 1.	0.918
MAP4K4	NCK2	ENSAPLP00000002786	ENSAPLP00000027386	Mitogen-activated protein kinase kinase kinase kinase 4.	Cytoplasmic protein.	0.426
MAP4K4	NRK	ENSAPLP00000002786	ENSAPLP00000013098	Mitogen-activated protein kinase kinase kinase kinase 4.	Uncharacterized protein.	0.901
MAP4K4	STRN3	ENSAPLP00000002786	ENSAPLP00000015955	Mitogen-activated protein kinase kinase kinase kinase 4.	Striatin 3.	0.576
MAP4K4	STRN4	ENSAPLP00000002786	ENSAPLP00000026621	Mitogen-activated protein kinase kinase kinase kinase 4.	Striatin 4.	0.576
MAP4K4	TBC1D8	ENSAPLP00000002786	ENSAPLP00000031525	Mitogen-activated protein kinase kinase kinase kinase 4.	TBC1 domain family member 8.	0.483
MAP4K4	TXN	ENSAPLP00000002786	ENSAPLP00000008437	Mitogen-activated protein kinase kinase kinase kinase 4.	Thioredoxin; Belongs to the thioredoxin family.	0.414
NCK2	MAP4K4	ENSAPLP00000027386	ENSAPLP00000002786	Cytoplasmic protein.	Mitogen-activated protein kinase kinase kinase kinase 4.	0.426
NCK2	NRK	ENSAPLP00000027386	ENSAPLP00000013098	Cytoplasmic protein.	Uncharacterized protein.	0.426
NRK	MAGI3	ENSAPLP00000013098	ENSAPLP00000002142	Uncharacterized protein.	Membrane associated guanylate kinase, WW and PDZ domain containing 3.	0.467
NRK	MAP3K1	ENSAPLP00000013098	ENSAPLP00000024275	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase 1.	0.908
NRK	MAP4K4	ENSAPLP00000013098	ENSAPLP00000002786	Uncharacterized protein.	Mitogen-activated protein kinase kinase kinase kinase 4.	0.901
NRK	NCK2	ENSAPLP00000013098	ENSAPLP00000027386	Uncharacterized protein.	Cytoplasmic protein.	0.426