GNB3 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

GNB3

G protein subunit beta 3. (331 aa)

Predicted Functional Partners:

CALCR

0.964

ADCY5

0.959

GPER1

0.953

GLP1R

0.947

U3IIF7_ANAPP

0.947

GABBR2

0.946

GNG11

0.946

HCRTR2

0.942

DRD1

0.941

GNGT2

0.940

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY5	GNB3	ENSAPLP00000005027	ENSAPLP00000002795	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	G protein subunit beta 3.	0.959
ADCY5	GNG11	ENSAPLP00000005027	ENSAPLP00000022549	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.957
ADCY5	GNGT2	ENSAPLP00000005027	ENSAPLP00000012380	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.954
CALCR	DRD1	ENSAPLP00000010135	ENSAPLP00000001291	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	0.492
CALCR	GNB3	ENSAPLP00000010135	ENSAPLP00000002795	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	G protein subunit beta 3.	0.964
CALCR	GNG11	ENSAPLP00000010135	ENSAPLP00000022549	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.948
CALCR	GNGT2	ENSAPLP00000010135	ENSAPLP00000012380	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.953
DRD1	CALCR	ENSAPLP00000001291	ENSAPLP00000010135	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	Calcitonin receptor; Belongs to the G-protein coupled receptor 2 family.	0.492
DRD1	GABBR2	ENSAPLP00000001291	ENSAPLP00000018220	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	Gamma-aminobutyric acid type B receptor subunit 2.	0.526
DRD1	GNB3	ENSAPLP00000001291	ENSAPLP00000002795	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	G protein subunit beta 3.	0.941
DRD1	GNG11	ENSAPLP00000001291	ENSAPLP00000022549	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.918
DRD1	GNGT2	ENSAPLP00000001291	ENSAPLP00000012380	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.924
GABBR2	DRD1	ENSAPLP00000018220	ENSAPLP00000001291	Gamma-aminobutyric acid type B receptor subunit 2.	Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family.	0.526
GABBR2	GNB3	ENSAPLP00000018220	ENSAPLP00000002795	Gamma-aminobutyric acid type B receptor subunit 2.	G protein subunit beta 3.	0.946
GABBR2	GNG11	ENSAPLP00000018220	ENSAPLP00000022549	Gamma-aminobutyric acid type B receptor subunit 2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.949
GABBR2	GNGT2	ENSAPLP00000018220	ENSAPLP00000012380	Gamma-aminobutyric acid type B receptor subunit 2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.956
GLP1R	GNB3	ENSAPLP00000004634	ENSAPLP00000002795	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	G protein subunit beta 3.	0.947
GLP1R	GNG11	ENSAPLP00000004634	ENSAPLP00000022549	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.937
GLP1R	GNGT2	ENSAPLP00000004634	ENSAPLP00000012380	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.938
GNB3	ADCY5	ENSAPLP00000002795	ENSAPLP00000005027	G protein subunit beta 3.	Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.959