STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLSCR5Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (211 aa)    
Predicted Functional Partners:
ANO6
Anoctamin.
      
 0.841
PLEKHN1
Pleckstrin homology domain containing N1.
    
 
 0.750
GATM
Glycine amidinotransferase.
    
 
 0.702
ACER2
Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
      
 0.633
ABCA2
ATP binding cassette subfamily A member 2.
      
 0.609
TMEM30A
Cell cycle control protein; Belongs to the CDC50/LEM3 family.
      
 0.601
SURF1
SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family.
    
 
 0.465
U3I3S3_ANAPP
Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
      
 0.457
ENSAPLP00000026605
PhoLip_ATPase_C domain-containing protein.
      
 0.457
ATP8B2
PhoLip_ATPase_C domain-containing protein.
      
 0.457
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.