Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PDLIM1PDZ and LIM domain 1. (327 aa)    
Predicted Functional Partners:
ACTN2
Actinin alpha 2.
   
 
 0.798
ACTN1
Actinin alpha 1.
   
 
 0.788
ACTN4
Actinin alpha 4.
   
 
 0.788
SH3RF3
SH3 domain containing ring finger 3.
    
 0.686
U3IS84_ANAPP
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
 
 0.641
GFAP
IF rod domain-containing protein; Belongs to the intermediate filament family.
   
 
 0.641
LDB3
LIM domain binding 3.
 
 
 
0.640
VCL
Vinculin.
   
 0.592
PDLIM5
PDZ and LIM domain 5.
   
 
0.588
ADCY1
Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.577
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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