Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ANKLE2Ankyrin repeat and LEM domain containing 2. (937 aa)    
Predicted Functional Partners:
VRK1
VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily.
   
 0.988
VRK2
VRK serine/threonine kinase 2.
   
 0.897
ENSAPLP00000024381
Uncharacterized protein.
   
 0.897
BANF1
Barrier to autointegration factor 1.
    
 0.865
PPP2CA
Serine/threonine-protein phosphatase.
    
 0.853
PPP2CB
Serine/threonine-protein phosphatase.
    
 0.853
ZNF335
Uncharacterized protein.
    
 0.730
ZNF335-2
Uncharacterized protein.
    
 0.730
LEMD2
LEM domain containing 2.
    
 0.707
NOLC1
Nucleolar and coiled-body phosphoprotein 1.
   
   0.696
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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