STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALKBH4AlkB homolog 4, lysine demethylase. (434 aa)    
Predicted Functional Partners:
KLHL31
Kelch like family member 31.
   
  
 0.844
HSF4
Heat shock transcription factor 4.
   
 
 0.740
D2HGDH
FAD-binding PCMH-type domain-containing protein.
      
 0.721
ERN2
Endoplasmic reticulum to nucleus signaling 2.
      
 0.687
HSF2
Heat shock transcription factor 2.
   
 
 0.642
APEX1
DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
 
      0.604
SHISA2
Shisa family member 2.
      
 0.597
METTL4
Methyltransferase like 4; Belongs to the MT-A70-like family.
      
 0.589
ALKBH1
AlkB homolog 1, histone H2A dioxygenase.
   
  
 0.573
MED28
Mediator complex subunit 28.
      
 0.536
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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