Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
RAB8BRAB8B, member RAS oncogene family. (339 aa)    
Predicted Functional Partners:
MICALL2
MICAL like 2.
    
 0.945
RAB8A
RAB8A, member RAS oncogene family.
  
  
 
0.901
RILPL2
Rab interacting lysosomal protein like 2.
   
 
 0.775
GDI2
Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.
   
 0.732
RAB3IP
Sec2p domain-containing protein.
    
 0.729
EHBP1
EH domain binding protein 1.
    
 0.709
EXOC5
Exocyst complex component 5.
   
 0.682
RILPL1
Rab interacting lysosomal protein like 1.
    
 0.680
EXOC2
Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
    
 0.678
RAB3IL1
RAB3A interacting protein like 1.
    
 0.604
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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