Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
    
 0.997
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
   
 0.991
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
  
0.990
U3IGX0_ANAPP
Uncharacterized protein.
   
 0.988
PIK3R2
Uncharacterized protein.
   
 0.987
PDPK1
3-phosphoinositide dependent protein kinase 1.
    
 0.981
PIK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
  
  
0.977
IRS4
Insulin receptor substrate 4.
   
 0.976
MTOR
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
0.976
IRS2
Insulin receptor substrate 2.
   
 0.976
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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