STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYKSpleen associated tyrosine kinase. (636 aa)    
Predicted Functional Partners:
PLCG2
Phosphoinositide phospholipase C.
   
0.982
CBLB
Cbl proto-oncogene B.
    
 0.976
CD3E
CD3e molecule.
   
 0.957
U3J954_ANAPP
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
0.956
CD247
CD247 molecule.
   
 0.956
ENSAPLP00000024741
Protein kinase domain-containing protein.
   
 0.933
BLNK
B cell linker.
   
 0.913
ENSAPLP00000032274
Protein kinase domain-containing protein.
  
 
0.894
CBL
Cbl proto-oncogene.
    
 0.890
VAV3
Vav guanine nucleotide exchange factor 3.
   
 0.868
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.