Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DENRDensity-regulated protein; Belongs to the DENR family. (182 aa)    
Predicted Functional Partners:
MCTS1
Malignant T-cell-amplified sequence.
   
 
 0.985
RWDD1
RWD domain containing 1.
   
    0.849
EIF1AY
S1-like domain-containing protein; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
   
 
 0.831
FAU
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
   0.831
RPS25
40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.
   
 
 0.827
EIF5
Eukaryotic translation initiation factor 5.
   
 
 0.816
COPS5
COP9 signalosome subunit 5.
   
 
 0.805
COPS4
COP9 signalosome subunit 4.
   
   0.783
EIF3J
Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
 
 0.780
ABCE1
ATP binding cassette subfamily E member 1.
   
 
 0.763
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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