| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ESR1 | KDM1A | ENSAPLP00000004132 | ENSAPLP00000010903 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.780 |
| ESR1 | NR3C2 | ENSAPLP00000004132 | ENSAPLP00000015040 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor subfamily 3 group C member 2. | 0.627 |
| ESR1 | NRIP1 | ENSAPLP00000004132 | ENSAPLP00000017856 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Nuclear receptor interacting protein 1. | 0.977 |
| ESR1 | TRIM24 | ENSAPLP00000004132 | ENSAPLP00000003258 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Tripartite motif containing 24. | 0.947 |
| ESR1 | TRIM33 | ENSAPLP00000004132 | ENSAPLP00000010241 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Tripartite motif containing 33. | 0.458 |
| ESR1 | UBE2I | ENSAPLP00000004132 | ENSAPLP00000016007 | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. | 0.671 |
| KDM1A | ESR1 | ENSAPLP00000010903 | ENSAPLP00000004132 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.780 |
| KDM1A | SETDB1 | ENSAPLP00000010903 | ENSAPLP00000018938 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | SET domain bifurcated histone lysine methyltransferase 1. | 0.496 |
| KDM1A | TRIM24 | ENSAPLP00000010903 | ENSAPLP00000003258 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Tripartite motif containing 24. | 0.776 |
| KDM1A | TRIM33 | ENSAPLP00000010903 | ENSAPLP00000010241 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Tripartite motif containing 33. | 0.901 |
| NR3C2 | ESR1 | ENSAPLP00000015040 | ENSAPLP00000004132 | Nuclear receptor subfamily 3 group C member 2. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.627 |
| NR3C2 | NRIP1 | ENSAPLP00000015040 | ENSAPLP00000017856 | Nuclear receptor subfamily 3 group C member 2. | Nuclear receptor interacting protein 1. | 0.401 |
| NR3C2 | TRIM24 | ENSAPLP00000015040 | ENSAPLP00000003258 | Nuclear receptor subfamily 3 group C member 2. | Tripartite motif containing 24. | 0.789 |
| NR3C2 | TRIM33 | ENSAPLP00000015040 | ENSAPLP00000010241 | Nuclear receptor subfamily 3 group C member 2. | Tripartite motif containing 33. | 0.508 |
| NR3C2 | UBE2I | ENSAPLP00000015040 | ENSAPLP00000016007 | Nuclear receptor subfamily 3 group C member 2. | Ubiquitin conjugating enzyme E2 I; Belongs to the ubiquitin-conjugating enzyme family. | 0.411 |
| NRIP1 | ESR1 | ENSAPLP00000017856 | ENSAPLP00000004132 | Nuclear receptor interacting protein 1. | Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. | 0.977 |
| NRIP1 | NR3C2 | ENSAPLP00000017856 | ENSAPLP00000015040 | Nuclear receptor interacting protein 1. | Nuclear receptor subfamily 3 group C member 2. | 0.401 |
| NRIP1 | SETDB1 | ENSAPLP00000017856 | ENSAPLP00000018938 | Nuclear receptor interacting protein 1. | SET domain bifurcated histone lysine methyltransferase 1. | 0.485 |
| NRIP1 | TRIM24 | ENSAPLP00000017856 | ENSAPLP00000003258 | Nuclear receptor interacting protein 1. | Tripartite motif containing 24. | 0.760 |
| NRIP1 | TRIM33 | ENSAPLP00000017856 | ENSAPLP00000010241 | Nuclear receptor interacting protein 1. | Tripartite motif containing 33. | 0.445 |