Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
GHRLGhrelin and obestatin prepropeptide. (116 aa)    
Predicted Functional Partners:
GHSR
Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.
    
 0.999
INS
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
     
 0.986
GH1
Uncharacterized protein.
   
 
 0.969
GCG
Glucagon.
   
 
 0.955
PYY
Peptide YY.
   
  
 0.935
CCK
Cholecystokinin.
     
 0.924
PCSK1
Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family.
     
 0.922
NPY
Neuropeptide Y.
   
  
 0.882
POMC
Proopiomelanocortin.
      
 0.858
MBOAT4
Uncharacterized protein; Belongs to the membrane-bound acyltransferase family.
     
 0.856
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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