STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (263 aa)    
Predicted Functional Partners:
CERS3
Ceramide synthase 3.
    
 0.964
U3I4F0_ANAPP
Neutral ceramidase.
    
 0.962
GBA2
Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.
     
 0.956
CERK
Ceramide kinase.
    
 0.954
SPHK1
Sphingosine kinase 1.
    
 0.945
SMPD1
Sphingomyelin phosphodiesterase 1.
     
 0.932
SGMS1
Sphingomyelin synthase 1.
     
 0.930
DEGS2
Delta 4-desaturase, sphingolipid 2.
   
 
 0.927
DEGS1
Delta 4-desaturase, sphingolipid 1.
   
 
 0.926
CERS5
Ceramide synthase 5.
    
 0.919
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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