Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CEP57Centrosomal protein 57. (519 aa)    
Predicted Functional Partners:
CEP63
CEP63 domain-containing protein.
   
 
 0.796
PLK4
Polo like kinase 4.
     
 0.739
CEP70
Centrosomal protein 70.
     
 0.720
PLK1
Serine/threonine-protein kinase PLK.
     
 0.716
DEUP1
Deuterosome assembly protein 1.
   
 
 0.699
CEP192
Centrosomal protein 192.
     
 0.695
TMLHE
Trimethyllysine hydroxylase, epsilon.
      
 0.671
CEP78
Centrosomal protein 78.
   
 
 0.624
CEP164
Centrosomal protein 164.
     
 0.623
CEP131
Centrosomal protein 131.
     
 0.610
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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