Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CCDC27Uncharacterized protein. (495 aa)    
Predicted Functional Partners:
KCTD10
Potassium channel tetramerization domain containing 10.
      
 0.664
TRIP11
Thyroid hormone receptor interactor 11.
      
 0.647
TP73
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
      
 0.616
ADGRV1
Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.
      
 0.547
BLZF1
Basic leucine zipper nuclear factor 1.
      
 0.546
ZPLD1
Zona pellucida like domain containing 1.
      
 0.544
SPERT
Uncharacterized protein.
   
  
 0.488
TNFAIP1
TNF alpha induced protein 1.
      
 0.481
PDZD7
PDZ domain-containing protein.
      
 0.464
ENSAPLP00000017270
Uncharacterized protein.
      
 0.464
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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