Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MLANAMelan-A. (113 aa)    
Predicted Functional Partners:
DCT
Dopachrome tautomerase.
   
  
 0.935
PMEL
Premelanosome protein.
   
  
 0.933
TYRP1
Tyrosinase related protein 1.
   
  
 0.851
GPR143
G protein-coupled receptor 143.
   
 
 0.788
MITF
Melanocyte inducing transcription factor.
    
 0.734
TYR
Tyrosinase.
      
 0.729
SLC24A5
Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
   
  
 0.719
SLC45A2
Solute carrier family 45 member 2.
   
  
 0.683
OCA2
OCA2 melanosomal transmembrane protein.
   
  
 0.658
ITCH
E3 ubiquitin-protein ligase.
    
   0.621
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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