Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIGTPhosphatidylinositol glycan anchor biosynthesis class T. (689 aa)    
Predicted Functional Partners:
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
   
 0.997
PIGS
Phosphatidylinositol glycan anchor biosynthesis class S.
   
 0.996
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
   
 0.995
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
   
 0.986
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
    
 0.953
PGAP1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
     
 0.942
PIGF
Phosphatidylinositol glycan anchor biosynthesis class F.
     
 0.928
PIGM
GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly.
      
 0.594
PIGV
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
    
 
 0.589
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
      
 0.562
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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