STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAK6Non-specific serine/threonine protein kinase. (693 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.993
NCK2
Cytoplasmic protein.
    
 0.963
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.956
RAC1
Rac family small GTPase 1.
   
 0.950
RAC3
Rac family small GTPase 3.
   
 0.950
RAC2
Rac family small GTPase 2.
   
 0.950
LIMK2
LIM domain kinase 2.
    
0.935
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
0.929
GNG12
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
  0.924
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
 
0.918
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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