Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PAK6Non-specific serine/threonine protein kinase. (693 aa)    
Predicted Functional Partners:
CDC42
Cell division cycle 42.
   
 0.992
NCK2
Cytoplasmic protein.
    
 0.968
RAC1
Rac family small GTPase 1.
   
 0.966
RAC2
Rac family small GTPase 2.
   
 0.966
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
    
 0.951
ARHGEF7
Rho guanine nucleotide exchange factor 7.
    
 0.951
LIMK2
LIM domain kinase 2.
    
0.933
ENSAPLP00000017111
Protein kinase domain-containing protein.
    
 0.933
RAF1
Raf-1 proto-oncogene, serine/threonine kinase.
    
 
0.932
MAP2K1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
  
 
0.925
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.