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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USPL1Ubiquitin specific peptidase like 1. (1088 aa)    
Predicted Functional Partners:
PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent [...]
    
 
 0.749
DESI1
Desumoylating isopeptidase 1.
      
 0.749
SUMO2
Small ubiquitin-related modifier.
    
 0.674
ENSAPLP00000029099
Ubiquitin-like domain-containing protein.
    
 0.674
ICE2
Interactor of little elongation complex ELL subunit 2.
   
 
 0.628
ENSAPLP00000024698
Uncharacterized protein.
   
 
 0.628
SUMO1
Small ubiquitin like modifier 1.
    
 0.612
PRPF6
Pre-mRNA processing factor 6.
      
 0.611
SENP5
SUMO specific peptidase 5.
   
 
 0.609
ENSAPLP00000026109
ULP_PROTEASE domain-containing protein.
   
 
 0.609
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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