STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECW1HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1. (1606 aa)    
Predicted Functional Partners:
RPS27A
Ubiquitin-like domain-containing protein.
    
  0.699
ARRDC1
Arrestin domain containing 1.
    
 
 0.669
DVL1
Dishevelled segment polarity protein 1.
    
 0.645
DVL3
Dishevelled segment polarity protein 3.
    
 0.645
ENSAPLP00000023897
Uncharacterized protein.
    
 0.642
PSMA2
Proteasome endopeptidase complex.
    
 0.606
ENSAPLP00000025536
Ubiquitin-like domain-containing protein.
    
 0.602
ERICH6B
FAM194 domain-containing protein.
    
 0.596
GJA1
Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
    
 0.592
SMAD6
Mothers against decapentaplegic homolog.
    
 0.575
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (20%) [HD]