STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM172AFamily with sequence similarity 172 member A. (416 aa)    
Predicted Functional Partners:
BRAF
B-Raf proto-oncogene, serine/threonine kinase.
      
 0.652
SLF1
SMC5-SMC6 complex localization factor 1.
      
 0.630
RSRC2
Arginine and serine rich coiled-coil 2.
      
 0.613
U3I5A4_ANAPP
Uncharacterized protein.
   
  
 0.564
RNPC3
RNA binding region (RNP1, RRM) containing 3.
      
 0.544
STX18
Syntaxin 18.
 
      0.486
CPPED1
Metallophos domain-containing protein.
      
 0.485
AGO3
Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
   
 
 0.466
AGO1
Argonaute RISC component 1; Belongs to the argonaute family.
   
 
 0.466
AGO4
Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily.
   
 
 0.466
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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