Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
TLR7Toll like receptor 7; Belongs to the Toll-like receptor family. (1089 aa)    
Predicted Functional Partners:
MYD88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.996
UNC93B1
Uncharacterized protein.
    
 0.945
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.897
IL6
Uncharacterized protein.
   
 
 0.859
CD4
Ig-like domain-containing protein.
   
 0.830
IRAK4
Interleukin 1 receptor associated kinase 4.
    
 0.800
TLR3
Toll like receptor 3; Belongs to the Toll-like receptor family.
    
0.779
IL10
Interleukin 10.
   
 
 0.774
IRF7
Interferon regulatory factor 7.
   
 
 0.772
IL18
Interleukin-18.
   
  
 0.763
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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