Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ALOX5APArachidonate 5-lipoxygenase activating protein. (161 aa)    
Predicted Functional Partners:
LGALS3
Galectin.
   
  
 0.892
LTA4H
Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.
      
 0.698
MAPK15
Mitogen-activated protein kinase.
      
 0.669
MGST1
Microsomal glutathione S-transferase 1.
      
 0.667
ALOX5
Arachidonate 5-lipoxygenase.
   
 
 0.628
PTGES
Prostaglandin E synthase.
      
 0.625
MGST3
Microsomal glutathione S-transferase 3.
      
 0.611
CD226
Ig-like domain-containing protein.
      
 0.604
RUSC2
RUN and SH3 domain containing 2.
      
 0.578
LTC4S-2
Uncharacterized protein.
   
 0.554
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.