PRPS2 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

PRPS2

Phosphoribosyl pyrophosphate synthetase 2. (325 aa)

Predicted Functional Partners:

PPAT

0.962

NUDT9

0.947

ENSAPLP00000019982

0.939

RPIA

0.934

PGM2

0.926

UMPS

0.910

NUDT5

0.908

ADPRM

0.904

ADSS1

0.774

BCKDHB

0.755

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADPRM	ENSAPLP00000019982	ENSAPLP00000031889	ENSAPLP00000019982	ADP-ribose/CDP-alcohol diphosphatase, manganese dependent.	Pribosyltran_N domain-containing protein.	0.904
ADPRM	NUDT5	ENSAPLP00000031889	ENSAPLP00000031623	ADP-ribose/CDP-alcohol diphosphatase, manganese dependent.	Nudix hydrolase 5; Belongs to the Nudix hydrolase family.	0.902
ADPRM	NUDT9	ENSAPLP00000031889	ENSAPLP00000002778	ADP-ribose/CDP-alcohol diphosphatase, manganese dependent.	Nudix hydrolase 9.	0.900
ADPRM	PGM2	ENSAPLP00000031889	ENSAPLP00000007997	ADP-ribose/CDP-alcohol diphosphatase, manganese dependent.	Phosphoglucomutase 2.	0.902
ADPRM	PRPS2	ENSAPLP00000031889	ENSAPLP00000003668	ADP-ribose/CDP-alcohol diphosphatase, manganese dependent.	Phosphoribosyl pyrophosphate synthetase 2.	0.904
ADSS1	ENSAPLP00000019982	ENSAPLP00000019532	ENSAPLP00000019982	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Pribosyltran_N domain-containing protein.	0.469
ADSS1	NUDT9	ENSAPLP00000019532	ENSAPLP00000002778	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Nudix hydrolase 9.	0.546
ADSS1	PGM2	ENSAPLP00000019532	ENSAPLP00000007997	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Phosphoglucomutase 2.	0.405
ADSS1	PPAT	ENSAPLP00000019532	ENSAPLP00000008829	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.771
ADSS1	PRPS2	ENSAPLP00000019532	ENSAPLP00000003668	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Phosphoribosyl pyrophosphate synthetase 2.	0.774
ADSS1	UMPS	ENSAPLP00000019532	ENSAPLP00000022193	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	Uridine monophosphate synthetase.	0.529
BCKDHB	ENSAPLP00000019982	ENSAPLP00000019242	ENSAPLP00000019982	Branched chain keto acid dehydrogenase E1 subunit beta.	Pribosyltran_N domain-containing protein.	0.755
BCKDHB	PRPS2	ENSAPLP00000019242	ENSAPLP00000003668	Branched chain keto acid dehydrogenase E1 subunit beta.	Phosphoribosyl pyrophosphate synthetase 2.	0.755
BCKDHB	RPIA	ENSAPLP00000019242	ENSAPLP00000019057	Branched chain keto acid dehydrogenase E1 subunit beta.	Ribose 5-phosphate isomerase A.	0.809
ENSAPLP00000019982	ADPRM	ENSAPLP00000019982	ENSAPLP00000031889	Pribosyltran_N domain-containing protein.	ADP-ribose/CDP-alcohol diphosphatase, manganese dependent.	0.904
ENSAPLP00000019982	ADSS1	ENSAPLP00000019982	ENSAPLP00000019532	Pribosyltran_N domain-containing protein.	Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.	0.469
ENSAPLP00000019982	BCKDHB	ENSAPLP00000019982	ENSAPLP00000019242	Pribosyltran_N domain-containing protein.	Branched chain keto acid dehydrogenase E1 subunit beta.	0.755
ENSAPLP00000019982	NUDT5	ENSAPLP00000019982	ENSAPLP00000031623	Pribosyltran_N domain-containing protein.	Nudix hydrolase 5; Belongs to the Nudix hydrolase family.	0.908
ENSAPLP00000019982	NUDT9	ENSAPLP00000019982	ENSAPLP00000002778	Pribosyltran_N domain-containing protein.	Nudix hydrolase 9.	0.906
ENSAPLP00000019982	PGM2	ENSAPLP00000019982	ENSAPLP00000007997	Pribosyltran_N domain-containing protein.	Phosphoglucomutase 2.	0.926