STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COLQCollagen like tail subunit of asymmetric acetylcholinesterase. (450 aa)    
Predicted Functional Partners:
BCHE
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
    
 
 0.925
PLOD1
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1.
   
 0.824
DOK7
Docking protein 7.
      
 0.818
PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2.
   
 0.778
MUSK
Muscle associated receptor tyrosine kinase.
    
 0.755
HACL1
2-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family.
 
      0.682
RAPSN
Receptor associated protein of the synapse.
      
 0.670
AGRN
Agrin.
    
 0.601
CHRNA1
Cholinergic receptor nicotinic alpha 1 subunit.
   
 
 0.577
SCN4A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
      
 0.568
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
Server load: medium (72%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.