KLF5 protein (Anas platyrhynchos) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

KLF5

Kruppel like factor 5. (446 aa)

Predicted Functional Partners:

WWP1

0.860

EP300

0.812

PIBF1

0.710

PPARG

0.671

CEBPB

0.647

RRP8

0.635

FBXW7

0.635

CREBBP

0.617

CEBPD

0.604

DAZL

0.593

Your Current Organism:

Anas platyrhynchos

NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CEBPB	CEBPD	ENSAPLP00000021900	ENSAPLP00000017410	CCAAT/enhancer-binding protein.	CCAAT enhancer binding protein delta.	0.772
CEBPB	CREBBP	ENSAPLP00000021900	ENSAPLP00000020073	CCAAT/enhancer-binding protein.	CREB binding protein.	0.737
CEBPB	EP300	ENSAPLP00000021900	ENSAPLP00000010252	CCAAT/enhancer-binding protein.	E1A binding protein p300.	0.879
CEBPB	KLF5	ENSAPLP00000021900	ENSAPLP00000003830	CCAAT/enhancer-binding protein.	Kruppel like factor 5.	0.647
CEBPB	PPARG	ENSAPLP00000021900	ENSAPLP00000008758	CCAAT/enhancer-binding protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.945
CEBPD	CEBPB	ENSAPLP00000017410	ENSAPLP00000021900	CCAAT enhancer binding protein delta.	CCAAT/enhancer-binding protein.	0.772
CEBPD	CREBBP	ENSAPLP00000017410	ENSAPLP00000020073	CCAAT enhancer binding protein delta.	CREB binding protein.	0.439
CEBPD	EP300	ENSAPLP00000017410	ENSAPLP00000010252	CCAAT enhancer binding protein delta.	E1A binding protein p300.	0.516
CEBPD	KLF5	ENSAPLP00000017410	ENSAPLP00000003830	CCAAT enhancer binding protein delta.	Kruppel like factor 5.	0.604
CEBPD	PPARG	ENSAPLP00000017410	ENSAPLP00000008758	CCAAT enhancer binding protein delta.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.839
CREBBP	CEBPB	ENSAPLP00000020073	ENSAPLP00000021900	CREB binding protein.	CCAAT/enhancer-binding protein.	0.737
CREBBP	CEBPD	ENSAPLP00000020073	ENSAPLP00000017410	CREB binding protein.	CCAAT enhancer binding protein delta.	0.439
CREBBP	EP300	ENSAPLP00000020073	ENSAPLP00000010252	CREB binding protein.	E1A binding protein p300.	0.999
CREBBP	KLF5	ENSAPLP00000020073	ENSAPLP00000003830	CREB binding protein.	Kruppel like factor 5.	0.617
CREBBP	PPARG	ENSAPLP00000020073	ENSAPLP00000008758	CREB binding protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.975
DAZL	KLF5	ENSAPLP00000007391	ENSAPLP00000003830	RRM domain-containing protein.	Kruppel like factor 5.	0.593
EP300	CEBPB	ENSAPLP00000010252	ENSAPLP00000021900	E1A binding protein p300.	CCAAT/enhancer-binding protein.	0.879
EP300	CEBPD	ENSAPLP00000010252	ENSAPLP00000017410	E1A binding protein p300.	CCAAT enhancer binding protein delta.	0.516
EP300	CREBBP	ENSAPLP00000010252	ENSAPLP00000020073	E1A binding protein p300.	CREB binding protein.	0.999
EP300	KLF5	ENSAPLP00000010252	ENSAPLP00000003830	E1A binding protein p300.	Kruppel like factor 5.	0.812