Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EGFL7EGF like domain multiple 7. (275 aa)    
Predicted Functional Partners:
CUTC
CutC copper transporter.
      
 0.590
EGF
Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
    
 0.576
CLDN5
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.
   
 
 0.565
FBXW2
F-box and WD repeat domain containing 2.
    
 0.531
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 
 0.493
SPRED1
Sprouty related EVH1 domain containing 1.
    
 
 0.479
ENSAPLP00000026620
Uncharacterized protein.
    
   0.462
UTS2
Urotensin 2.
     
 0.446
KBTBD3
Kelch repeat and BTB domain containing 3.
      
 0.442
ITGA4
Integrin subunit alpha 4; Belongs to the integrin alpha chain family.
    
 0.416
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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