STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEDD4E3 ubiquitin-protein ligase. (875 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.927
SMURF1
E3 ubiquitin-protein ligase.
    
0.919
CBLB
Cbl proto-oncogene B.
    
 0.918
CBL
Cbl proto-oncogene.
    
 0.918
WWP1
E3 ubiquitin-protein ligase.
    
0.916
ITCH
E3 ubiquitin-protein ligase.
  
 
0.915
MDM2
Uncharacterized protein.
    
 0.910
DLG3
Discs large MAGUK scaffold protein 3.
    
  0.910
NEDD4L
NEDD4 like E3 ubiquitin protein ligase.
  
  
 
0.901
EGFR
Receptor protein-tyrosine kinase.
    
 0.812
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.