Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLK1Tousled like kinase 1. (725 aa)    
Predicted Functional Partners:
TLK2
Tousled like kinase 2.
   
   0.993
ASF1A
Anti-silencing function 1A histone chaperone.
    
 
 0.975
ENSAPLP00000019469
Uncharacterized protein.
    
   0.695
POLG
DNA polymerase gamma, catalytic subunit.
      
 0.670
PRIM1
DNA primase; Belongs to the eukaryotic-type primase small subunit family.
      
 0.652
METAP1D
Methionine aminopeptidase; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
      
 0.651
MBP
Myelin basic protein.
    
 
 0.649
CABIN1
TPR_REGION domain-containing protein.
    
 
 0.634
ENSAPLP00000029227
MEF2_binding domain-containing protein.
    
 
 0.634
HIRA
Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.
    
 
 0.592
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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