Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MAP3K14Mitogen-activated protein kinase kinase kinase 14. (944 aa)    
Predicted Functional Partners:
CHUK
Component of inhibitor of nuclear factor kappa B kinase complex.
   
0.998
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.998
IKBKB
Inhibitor of nuclear factor kappa B kinase subunit beta.
   
0.997
MAP3K8
Mitogen-activated protein kinase kinase kinase 8.
    
0.994
TRAF2
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.988
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
    
0.956
TRAF5
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.927
TRAF6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.896
TRAF1
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.891
BIRC2
Uncharacterized protein.
    
 0.875
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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