Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MSMO1Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (296 aa)    
Predicted Functional Partners:
NSDHL
NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family.
   
 0.990
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 0.989
DHCR24
24-dehydrocholesterol reductase.
   
 
 0.978
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.978
LBR
Lamin B receptor.
   
 0.968
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 
 0.907
SQLE
SE domain-containing protein.
   
 
 0.872
ENSAPLP00000028634
FAD_binding_3 domain-containing protein.
   
 
 0.872
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
   
  
 0.865
DHCR7
7-dehydrocholesterol reductase.
   
 0.836
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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