Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
UBE3BUbiquitin protein ligase E3B. (1070 aa)    
Predicted Functional Partners:
ZRANB1
Zinc finger RANBP2-type containing 1.
      
 0.738
PUDP
Pseudouridine 5'-phosphatase.
      
 0.603
SDE2
SDE2 telomere maintenance homolog.
      
 0.595
TRIP12
Thyroid hormone receptor interactor 12.
      
 0.565
FBXO9
F-box protein 9.
      
 0.564
NDUFAF7
Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
      
 0.556
RPS27A
Ubiquitin-like domain-containing protein.
    
  0.549
DLK1
Delta like non-canonical Notch ligand 1.
    
   0.538
UBA5
Ubiquitin like modifier activating enzyme 5.
     
 0.529
ATG7
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...]
     
  0.525
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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