Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
XRCC6X-ray repair cross complementing 6. (617 aa)    
Predicted Functional Partners:
XRCC5
X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.
  
 0.999
PRKDC
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
   
 0.997
LIG4
DNA ligase.
   
 0.991
DCLRE1C
DNA cross-link repair 1C.
    
 0.986
U3I2H1_ANAPP
Uncharacterized protein.
   
 
 0.979
LIG3
DNA ligase.
   
 0.976
ATM
Non-specific serine/threonine protein kinase.
    
 0.974
ENSAPLP00000026881
Zinc-hook domain-containing protein.
   
 0.972
APLF
Aprataxin and PNKP like factor.
    
 
 0.971
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.967
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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