Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGB3Integrin beta; Belongs to the integrin beta chain family. (1055 aa)    
Predicted Functional Partners:
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
   
 0.999
FN1
Fibronectin 1.
    
 0.996
THBS1
Thrombospondin 1.
   
 0.985
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
   
 0.980
ITGA8
Integrin subunit alpha 8; Belongs to the integrin alpha chain family.
   
 0.980
PTK2
Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 0.976
U3I5C9_ANAPP
Uncharacterized protein.
    
 0.973
FLNB
Filamin B.
    
 0.970
VWF
Von Willebrand factor.
   
 0.969
THBS2
Thrombospondin 2.
   
 0.966
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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