STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
APPL1Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (696 aa)    
Predicted Functional Partners:
ADIPOR1
Adiponectin receptor 1.
    
 0.980
ADIPOR2
Adiponectin receptor 2.
    
 0.980
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
 0.948
DCC
DCC netrin 1 receptor.
    
 0.930
IGDCC4
Immunoglobulin superfamily DCC subclass member 4.
    
 0.930
NEO1
Neogenin 1.
    
 0.930
IGDCC3
Immunoglobulin superfamily DCC subclass member 3.
    
 0.930
STK11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.924
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.826
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 
 0.826
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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