Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TLN1Talin 1. (2594 aa)    
Predicted Functional Partners:
VCL
Vinculin.
   
 0.999
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.962
TLN2
Talin 2.
  
 
 
0.954
ITGB5
Integrin beta; Belongs to the integrin beta chain family.
   
 0.949
CAPN2
Calpain 2; Belongs to the peptidase C2 family.
   
 0.935
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.933
ITGA1
Integrin subunit alpha 1; Belongs to the integrin alpha chain family.
    
 0.928
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
   
 0.920
ITGB8
Integrin beta; Belongs to the integrin beta chain family.
   
 0.910
ITGB4
Integrin beta.
   
 0.868
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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