STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AMPD3AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (683 aa)    
Predicted Functional Partners:
ADSL
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
     
 0.974
ADSS1
Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.970
ADSS2
Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.968
APRT
Adenine phosphoribosyltransferase.
   
 0.965
ITPA
Inosine triphosphatase.
  
 
 0.963
ADK
Adenosine kinase.
    
 0.962
NT5M
5',3'-nucleotidase, mitochondrial.
     
 0.958
ENTPD5
Ectonucleoside triphosphate diphosphohydrolase 5 (inactive); Belongs to the GDA1/CD39 NTPase family.
   
 
 0.958
ENTPD4
Ectonucleoside triphosphate diphosphohydrolase 4; Belongs to the GDA1/CD39 NTPase family.
     
 0.958
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
    
 0.955
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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