STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
U3IA28_ANAPPProtein kinase domain-containing protein. (444 aa)    
Predicted Functional Partners:
LRRK1
Leucine rich repeat kinase 1.
    
 0.781
SCN3A
Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
    
 0.621
CTXN1
Cortexin 1.
      
 0.611
SULT4A1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.609
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
   
 0.571
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.544
PDZRN4
PDZ domain containing ring finger 4.
   
 0.487
PROX2
Prospero homeobox 2.
      
 0.487
ESRRG
Estrogen related receptor gamma.
    
 0.462
BIRC6
Baculoviral IAP repeat containing 6.
   
 0.446
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.