STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (548 aa)    
Predicted Functional Partners:
ESR2
Estrogen receptor 2.
  
 
0.979
EP300
E1A binding protein p300.
    
 0.953
PGR
Progesterone receptor.
   
0.926
ATAD2
ATPase family AAA domain containing 2.
    
 0.920
BRCA1
BRCA1 DNA repair associated.
    
 
 0.920
PTGES3
Prostaglandin E synthase 3.
   
 0.913
SP1
Sp1 transcription factor.
    
 0.912
NRIP1
Nuclear receptor interacting protein 1.
    
 0.910
CREBBP
CREB binding protein.
    
 0.889
ENSAPLP00000030173
Uncharacterized protein.
    
 0.878
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.