Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1105 aa)    
Predicted Functional Partners:
GDNF
Glial cell derived neurotrophic factor.
    
 0.994
GFRA2
GDNF family receptor alpha 2.
    
 0.993
NRTN
Neurturin.
    
 0.990
GRB2
Growth factor receptor bound protein 2.
    
 0.971
STAT3
Signal transducer and activator of transcription.
    
 0.936
GFRAL
GDNF family receptor alpha like.
    
 0.931
ENSAPLP00000025629
IRS-type PTB domain-containing protein.
    
  0.920
GFRA1
GDNF family receptor alpha-1; Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. Belongs to the GDNFR family.
    
 0.915
PLCG1
Phosphoinositide phospholipase C.
    
 0.873
PLCG2
Phosphoinositide phospholipase C.
    
 0.873
Your Current Organism:
Anas platyrhynchos
NCBI taxonomy Id: 8840
Other names: A. platyrhynchos platyrhynchos, Anas platyrhynchos platyrhynchos, common mallard, northern mallard
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